Norepinephrine inhibition of vasopressin antidiuresis
نویسندگان
چکیده
منابع مشابه
Norepinephrine inhibition of vasopressin antidiuresis.
The effect of norepinephrine on exogenous vasopressin antidiuresis was investigated in water-loaded subjects. After an initial 2 to 3 hr period of water loading (phase 1), 10-100 mU of vasopressin per hr were infused at a constant rate for 1 hr (phase 2) followed by infusion of 10-100 mU of vasopressin per hr plus 600 mug of l-norepinephrine per hr for 1 hr (phase 3). Endogenous creatinine clea...
متن کاملEscape from vasopressin-induced antidiuresis: role of vasopressin resistance of the collecting duct.
Previously, we demonstrated that escape from vasopressin-induced antidiuresis ("vasopressin escape") in rats is associated with a large, selective decrease in whole kidney expression of aquaporin-2, the vasopressin-regulated water channel. Here, we show that isolated perfused inner medullary collecting ducts (IMCDs) from vasopressin-escape rats {desamino-[d-arginine]vasopressin (DDAVP)/water-lo...
متن کاملSex differences in vasopressin V₂ receptor expression and vasopressin-induced antidiuresis.
The renal vasopressin V(2) receptor (V(2)R) plays a critical role in physiological and pathophysiological processes associated with arginine vasopressin (AVP)-induced antidiuresis. Because clinical data suggests that females may be more prone to hyponatremia from AVP-mediated antidiuresis, we investigated whether there are sex differences in the expression and function of the renal V(2)R. In no...
متن کاملSex differences in vasopressin V2 receptor expression and vasopressin-induced antidiuresis
Liu J, Sharma N, Zheng W, Ji H, Tam H, Wu X, Manigrasso MB, Sandberg K, Verbalis JG. Sex differences in vasopressin V2 receptor expression and vasopressin-induced antidiuresis. Am J Physiol Renal Physiol 300: F433–F440, 2011. First published December 1, 2010; doi:10.1152/ajprenal.00199.2010.—The renal vasopressin V2 receptor (V2R) plays a critical role in physiological and pathophysiological pr...
متن کاملVasopressin V2 receptor binding is down-regulated during renal escape from vasopressin-induced antidiuresis.
This study evaluated whether renal escape from vasopressin-induced antidiuresis is associated with alterations of vasopressin V2 receptor binding in the kidney inner medulla. A radioligand binding assay was developed using a novel iodinated vasopressin V2 receptor antagonist to analyze vasopressin V2 receptor binding in kidney inner medullary tissue from three groups of rats: normal rats mainta...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1968
ISSN: 0021-9738
DOI: 10.1172/jci105750