NONSPECIFIC PROTEIN THERAPY

Exercise therapy for chronic nonspecific low-back pain.

Exercise therapy is the most widely used type of conservative treatment for low back pain. Systematic reviews have shown that exercise therapy is effective for chronic but not for acute low back pain. During the past 5 years, many additional trials have been published on chronic low back pain. This articles aims to give an overview on the effectiveness of exercise therapy in patients with low b...

Effectiveness of exercise therapy in reducing pain and disability in athletes with chronic nonspecific neck pain

Aims and background: Chronic neck pain is a common problem and is often associated with changes in sensory-motor functions such as decreased neck proprioception, altered neck muscle coordination, and increased postural fluctuations. The aim of this study was the effectiveness of exercise therapy in improving chronic non-specific neck pain in athletes in Khorramabad. Methods and Materials: The ...

Nonspecific DNA bending and the specificity of protein-DNA interactions.

Mitochondrial outer membrane contains a protein producing nonspecific diffusion channels.

Vesicles permeable to sucrose, but not to high molecular weight dextrans, were produced when fragments of mitochondrial outer membrane obtained from rat liver or mung bean seedlings were fused with liposomes of soybean phospholipids. By using this reconstitution assay, the channel-forming protein in the mung bean mitochondria was identified as protein(s) with an apparent molecular weight of 30,...

Nonspecific DNA-protein interaction: why proteins can diffuse along DNA.

Recent single molecule experiments have reported that DNA binding proteins (DNA-BPs) can diffuse along DNA. This suggests that interactions between proteins and DNA play a role during the target search even far from their specific site on DNA. Here we show by means of Monte Carlo simulations and analytical calculations that there is a counterintuitive repulsion between the two oppositely charge...