Nonsense‐mediated mRNA decay involves two distinct Upf1‐bound complexes
نویسندگان
چکیده
منابع مشابه
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The tristetraprolin (TTP) family of zinc-finger proteins, TTP, BRF1 and BRF2, regulate the stability of a subset of mRNAs containing 3'UTR AU-rich elements (AREs), including mRNAs coding for cytokines, transcription factors, and proto-oncogenes. To better understand the mechanism by which TTP-family proteins control mRNA stability in mammalian cells, we aimed to identify TTP- and BRF1-interacti...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2018
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.201899278