Nonselective ß-blocker propranolol for orbital and periorbital hemangiomas in infants: a new first-line of treatment?

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Nonselective β-blocker propranolol for orbital and periorbital hemangiomas in infants: a new first-line of treatment?

PURPOSE To determine the effectiveness and possible side effects of using propranolol for the treatment of orbital and periorbital infantile hemangiomas. METHODS Infants with periorbital or orbital hemangiomas who had not received either local or systemic corticosteroids were recruited. The changes in tumor size, color, and texture, and any side effects of the drug were recorded. RESULTS Fi...

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Propranolol as first-line treatment of head and neck hemangiomas.

OBJECTIVES To report the efficacy of propranolol as first-line treatment of head and neck hemangiomas in children and to present an optimized protocol for treating hemangiomas. DESIGN Multi-institutional retrospective study. SETTING Two tertiary care referral pediatric centers. PATIENTS Thirty-nine children with head and neck infantile hemangiomas were treated. MAIN OUTCOME MEASURES Rev...

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Nonselective (Propranolol) Beta-adrenergic Blocker

delayed repolarization syndromes. Mod Concepts Cardiovasc Dis 45: 117, 1976 28. Castellanos A, Salhanick L: Electrocardiographic patterns of procainamide cardiotoxicity. Am J Med Sci 253: 52, 1967 29. Epstein MA: Ventricular standstill during the intravenous procainamide treatment of ventricular tachycardia. Am Heart J 45: 890, 1953 30. Seiklos P, Chalme TM, Evans DW: Ventricular tachycardia af...

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Combined low-dose oral propranolol and oral prednisolone as first-line treatment in periocular infantile hemangiomas.

PURPOSE The purpose of this report was to describe 2 cases of periocular infantile hemangiomas (IHs) that were successfully treated with low-dose oral propranolol alone and in combination with oral prednisolone. METHODS Two infants aged 3 months and 6 weeks, respectively, were referred for management of vision-threatening periocular IHs causing ocular displacement and obscuration of the visua...

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Propranolol for treatment of infantile hemangiomas*

Infantile hemangioma is the most common vascular tumor in early childhood. Propranolol has been successfully used recently in a limited number of children with Infantile hemangioma. We present 6 cases of Infantile hemangioma, at a single dermatological center, which responded to oral propranolol with good results.

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2011

ISSN: 1177-5483

DOI: 10.2147/opth.s24141