Nonlinear dynamics of cardiac excitation-contraction coupling: An iterated map study
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چکیده
منابع مشابه
Nonlinear dynamics of cardiac excitation-contraction coupling: an iterated map study.
Cardiac myocytes are excitable cells in which an external current stimulus depolarizes the membrane potential to elicit an action potential. This action potential then triggers calcium release from intracellular stores, which mediates contraction. Conversely, intracellular calcium also modulates membrane currents, affecting action potential morphology and action potential duration (APD). The in...
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It is well established that excitation contraction (EC) coupling in cardiac myocytes is mediated by the entry of calcium ions (Ca 2 ) from the bathing medium into the cell cytoplasm (Fabiato, 1985), which then triggers calcium-induced calcium release (CICR) from the sarcoplasmic reticulum (SR). More recently, it was proposed that a second, quite separate, EC-coupling process, mediated by an eff...
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gitudinal system of the SR, governing the Ca storage compartment with the highest recruitable amount of Ca in cardiac myocytes. The RyR are chemically coupled to L-type Ca channels via Ca, and a relatively small amount of Ca entering the cell via L-type Ca channels (depending on species or stimulation rate) activates a limited number of adjacent RyRs. This leads to Ca release from the SR, and a...
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gitudinal system of the SR, governing the Ca storage compartment with the highest recruitable amount of Ca in cardiac myocytes. The RyR are chemically coupled to L-type Ca channels via Ca, and a relatively small amount of Ca entering the cell via L-type Ca channels (depending on species or stimulation rate) activates a limited number of adjacent RyRs. This leads to Ca release from the SR, and a...
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Heart Failure After Myocardial Infarction : Altered Excitation-Contraction Coupling Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2001 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/hc3201.092285 2001;104:688-693 Circulation. http://circ.ahajournals.org/content/10...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2007
ISSN: 1539-3755,1550-2376
DOI: 10.1103/physreve.75.011927