Noninvasive MRI Measurement of CBF: Evaluating An Arterial Spin Labelling Sequence with 99mTc-HMPAO CBF Autoradiography in a Rat Stroke Model
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منابع مشابه
Noninvasive MRI measurement of CBF: evaluating an arterial spin labelling sequence with 99mTc-HMPAO CBF autoradiography in a rat stroke model.
Arterial spin labelling (ASL) is increasingly available for noninvasive cerebral blood flow (CBF) measurement in stroke research. Here, a pseudo-continuous ASL technique (pCASL) was evaluated against (99m)Tc-D, L-hexamethylpropyleneamine oxime ((99m)Tc-HMPAO) autoradiography in a rat stroke model. The (99m)Tc-HMPAO was injected (intravenously, 225 MBq) during pCASL acquisition. The pCASL and (9...
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simulated increased activation of ΔCBF =50% of baseline centered on a 100% GM voxel. The following images (left to right) show results from the PVE-corrected method with kernel sizes of 3x3, 5x5, 9x9, 11x11, 13x13, respectively. Note the dilution effect of the larger kernels. Fig.3: Images of: SPGR (left) and PVE-corrected CBF (right). Note good detection of the ischemic region. The observed le...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2012
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.2012.19