NONFLUORIDATED REMINERALIZING AGENTS

Early diagnosis of dental caries is paramount importance. If we are able to intercept lesion at subsurface level with the help remineralizing agents, can actually achieve a free mouth.Remineralization was ruled by fluorides from 1960s. Since then it has been successfully carious lesions & certain disadvantages like dependant on calcium and phosphate saliva accomplish this. Also overuse cause skeletal fluorosis. This made researchers explore nonfluoridated agents.ACP compounds considered prime candidates for remineralization therapy due their high solubility under oral conditions ability rapidly hydrolyze form apatite. Casein phospho-peptides responsible bioavailability milk other dairy products. CPP have bind stabilize in solution, as well plaque tooth enamel. ACP, localize ACP plaque, thereby maintaining state supersaturation respect enamel, reducing demineralization. TCP new hybrid material when comes into contact surface moistened saliva, protective barrier breaks down making calcium, fluoride ions available tooth. Xylitol, sugar substitute especially chewing gums which increases salivary flow rate enhances properties saliva. Bioactive glass synthetic mineral containing sodium, phosphorous silica all elements naturally found body. Ozone shift microbial flora acidogenic bacteria normal commensals allowing occur. Nanohydroxyapatite, bioactive biocompatible material, functions directly filling up micropores early lesions.On basis data authors given an insight different agents this article.