Non-steroidal analgesic and anti-inflammatory agents.

Anti-inflammatory and Analgesic Agents

Inflammatory diseases including arthritis and rheumatism are major group of prevalent diseases. Most of the available non-steroidal anti-inflammatory drugs are effective in inflammatory conditions of the joints, but are devoid of gastro protective property. Many substances, interfering with the inflammatory response have been isolated from Indian medicinal plants (IMP). The review analyses form...

Peptic ulcer and non-steroidal anti-inflammatory agents.

Aspirin is generally regarded as a cause of gastric ulcer but the role of non-steroidal anti-inflammatory agents and paracetamol in the aetiology of peptic ulcer is unclear. To investigate this we conducted a case control study of 180 matched pairs of peptic ulcer patients and controls obtained from surgical and dermatology outpatient clinics. There were 95 gastric ulcer and 85 duodenal ulcer p...

Non-steroidal anti-inflammatory agents and the gastrointestinal tract.

The chemistry of non-steroidal anti-inflammatory agents.

It is not possible to discuss immediately the chemistry of, and the therapeutic response to, anti-inflammatory agents which do not possess the steroidal skeleton without properly defining the terms. It is even more fundamental, but entirely in order, to make some introductory remarks concerning those small molecules, normally dubbed 'drugs', which are designed to combat diseases of major import...

Non-steroidal anti-inflammatory drugs.