Non-specific immune response of Pacific white shrimp Litopenaeus vannamei by supplementation of sodium alginate of Sargassum collected from Lampung Indonesia

Abstract This study aims to determine the effectiveness of supplementation sodium (Na) alginate Sargassum sp. from Lampung waters enhance non-specific immune response and resistence Pacific white shrimp ( Litopenaeus vannamei ) against spot disease. used a completely randomized design with 3 treatments, namely feeding without (A) or control, dietary Na at dose 2.0 (B), 4.0 g kg −1 feed (C), each four replications, for 14 days. Hemolymph sampling was performed on days 0, 7 observe parameter hematology included total haemocyte count (THC), phagocytocyte activity (PA), phagocytic index (PI), plasma protein (TPP). The hepatopancreas histology profile water quality were observed end treatment. Data analyzed by Anova 95% confidence interval continued Duncan test. Result showedthat alginat significantly several THC, PA, TPP. Meanwhile, both treatment control showed not effect tissue damage. still in normal condition during results this indicate that application 2gr/kg is best shrimp.