Non-small cell lung cancer - genetic predictors
نویسندگان
چکیده
منابع مشابه
Genetic predictors of MEK dependence in non-small cell lung cancer.
Hyperactivated extracellular signal-regulated kinase (ERK) signaling is common in human cancer and is often the result of activating mutations in BRAF, RAS, and upstream receptor tyrosine kinases. To characterize the mitogen-activated protein kinase/ERK kinase (MEK)/ERK dependence of lung cancers harboring BRAF kinase domain mutations, we screened a large panel of human lung cancer cell lines (...
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ژورنال
عنوان ژورنال: Biomedical Papers
سال: 2013
ISSN: 1213-8118,1804-7521
DOI: 10.5507/bp.2013.034