Non-pigmenting Fixed Drug Eruption Induced by Sorafenib

Non-pigmenting fixed drug eruption induced by sorafenib.

Non-pigmenting cutaneous-mucosal fixed drug eruption due to piroxicam.

BACKGROUND Piroxicam is a widely used anti-inflammatory drug. Most adverse reactions affect gastrointestinal system, liver and skin. Fixed drug eruption although very unusual, has also been described, but with cutaneous involvement exclusively. We present the case of a 49-year-old man who suffered three episodes of fixed drug eruption with cutaneous-mucosal involvement, even simulating an autoi...

Fixed Drug Eruption Induced by Levocetirizine

Fixed drug eruption induced by atenolol

Fixed drug eruption (FDE) is characterized by recurrent well-defined lesions in the same location each time the responsible drug is taken. We report here a case of multiple FDE induced by atenolol in a 48-year-old woman confirmed by positive patch test in previously affected sites. Beta-blockers-induced FDE are very rare. Only two cases had been reported in the literature. To the best of our kn...

Nimesulide-induced fixed drug eruption.

BACKGROUND Nimesulide is a cyclooxygenase (COX) inhibitor with a high degree of selectivity to COX-2. It is a widely used and well tolerated nonsteroidal antiinflammatory drug that also has analgesic and antipyretic properties. The most frequently reported side effects concern the gastrointestinal tract. Pruritus and skin rash are the most common cutaneous adverse reactions. There are only eigh...