Non-iminosugar glucocerebrosidase small molecule chaperones
نویسندگان
چکیده
منابع مشابه
Non-iminosugar glucocerebrosidase small molecule chaperones.
Small molecule chaperones are a promising therapeutic approach for the Lysosomal Storage Disorders (LSDs). Here, we report the discovery of a new series of non-iminosugar glucocerebrosidase inhibitors with chaperone capacity, and describe their structure activity relationship (SAR), selectivity, cell activity phamacokinetics.
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ژورنال
عنوان ژورنال: Med. Chem. Commun.
سال: 2012
ISSN: 2040-2503,2040-2511
DOI: 10.1039/c1md00200g