Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins
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چکیده
منابع مشابه
Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins
Schlafen11 (encoded by the SLFN11 gene) has been shown to inhibit the accumulation of HIV-1 proteins. We show that the SLFN11 gene is under positive selection in simian primates and is species-specific in its activity against HIV-1. The activity of human Schlafen11 is relatively weak compared to that of some other primate versions of this protein, with the versions encoded by chimpanzee, orangu...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2016
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1006066