NON-DEPOLARIZING RELAXANTS AND LIVER DISEASE
نویسندگان
چکیده
منابع مشابه
Changes in resistance to mouth opening induced by depolarizing and non-depolarizing neuromuscular relaxants.
Mouth opening was measured in 43 children anaesthetized with isoflurane and paralysed with vecuronium or suxamethonium. Measurements of mouth opening were made for up to 10 min after loss of the adductor pollicis twitch and cessation of muscle fasciculations. In 22 patients receiving suxamethonium, a significant (P less than 0.001) reduction in mean mouth opening occurred in the 60 s after loss...
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The chemical theory of neuromuscular transmission (Dale, Feldberg and Vogt, 1936) is now almost universally accepted, and implicates acetylcholine as the neuromuscular transmitter. Depolarizing muscle relaxants act, at least initially, in a manner similar to acetylcholine and are believed to produce their effects by prolonged depolarization, but in certain situations these agents, instead of pr...
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Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic steatohepatitis (NASH) and cirrhosis in Iran. M...
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The interaction of four inhalational anesthetics (sevoflurane, isoflurane, enflurane and halothane) with pancuronium and vecuronium and also their prejunctional actions at the neuromuscular junction were quantitatively studied using rat phrenic nerve-hemidiaphragm preparations. To investigate the prejunctional effects of inhalational anesthetics, a train-of-four ratio (T4/T1) and the tetanus ra...
متن کاملDifferent magnitude of resistance to non-depolarizing muscle relaxants in dexamethasone-treated rat diaphragm associated with altered acetylcholine receptor expression.
The aim of this study was to investigate the influence of chronic dexamethasone (Dex) administration on rat diaphragm sensitivity to non-depolarizing muscle relaxants (NDMRs) and muscular nicotinic acetylcholine receptor (nAChR) expression, which may help direct future administration of NDMRs. Adult male Sprague-Dawley rats were randomized to receive a daily intraperitoneal injection of Dex (60...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1978
ISSN: 0007-0912
DOI: 10.1093/bja/50.6.635-b