Non-conventional hormone therapy - Tissue-specific Tibolone-Caution

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منابع مشابه

Mammographic density in postmenopausal women treated with tibolone, estriol or conventional hormone replacement therapy.

OBJECTIVE To compare the effects of tibolone, estriol and conventional hormone replacement therapy (HRT) on mammographic parenchymal density in postmenopausal women. DESIGN AND SETTING This was a non-randomised, prospective, longitudinal, comparative study conducted at two specialist outpatient clinics in Chile. PATIENTS AND PARTICIPANTS 210 non-obese, postmenopausal women aged <65 years wi...

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Tibolone and the promise of ideal hormone-replacement therapy.

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Postmenopausal hormone replacement therapy with Tibolone decreases serum lipoprotein(a).

Lipoprotein(a) is a cholesterol-rich plasma lipoprotein consisting of LDL and apolipoprotein(a). Apolipoprotein(a) shows structural similarity with plasminogen and thus may interfere with thrombogenesis. Lipoprotein(a) has been shown to be a strong independent risk factor for coronary heart disease. So far no drug or diet is known to have prominent effects on the serum levels of lipoprotein(a)....

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Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone

We present the case report of a patient with severe polycythaemia associated with tibolone. In our 65-year-old postmenopausal patient who initially presented with haemoglobin 203 g/L [115-160] and haematocrit 0.63 [0.32-0.47], the cessation of tibolone, a synthetic hormone replacement therapy, led to a dramatic and sustained resolution of this patient's polycythaemia to normal haematological va...

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Tibolone : A Selective Tissue Estrogenic Activity Regulator

Tibolone is a STEAR (Selective tissue estrogenic activity regulator) (1). It is a synthetic steroid with tissue selectivity that has progestogenic, some androgenic as well as estrogenic effects. It has been used as an alternative to estrogen replacement therapy in several European countries for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and treatment of climac...

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ژورنال

عنوان ژورنال: Journal of Mid-life Health

سال: 2010

ISSN: 0976-7800

DOI: 10.4103/0976-7800.76213