Non-Coding RNAs in Psychiatric Disorders and Suicidal Behavior

The Role of Long Non-Coding RNAs in Ovarian Cancer

Background: Ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. Various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. However, the aim of this review was to investigate the role of long non-co...

Long non-coding RNAs and their significance in human diseases

Protein-coding genes account for only a small fraction of the human genome and most of the genomic sequences are transcriptionally silent, but recent observations indicate significant functional elements, including non-coding protein transcripts in the human genome. Long non-coding RNAs (lncRNAs) have been defined as transcripts of >200 nucleotides without protein-coding capacity that perform t...

Editorial: Non-Coding RNAs in Neurodevelopmental Disorders

Long non-coding RNAs in neurodevelopmental disorders

Recent studies have emphasized an important role for long non-coding RNAs (lncRNA) in epigenetic regulation, development, and disease. Despite growing interest in lncRNAs, the mechanisms by which lncRNAs control cellular processes are still elusive. Improved understanding of these mechanisms is critical, because the majority of the mammalian genome is transcribed, in most cases resulting in non...

comparison of personality traits, coping styles, and psychiatric disorders in adult suicidal and non-suicidal individuals

background: suicide is a major health problem accounting for 9% of all deaths. thus, suicide prevention is of particular importance in high-risk groups. taking care of the individuals who have committed suicide is also considered as a major problem for health professionals. in general, individuals’ personality and attitude toward problems are involved in the incidence of suicide. human personal...