“Non-canonical protein-DNA interactions identified by ChIP are not artifacts”: response
نویسندگان
چکیده
منابع مشابه
Analyzing DNA-protein interactions on a chip
Gene expression is regulated by multi-protein complexes binding to short non-coding regions of genomic DNA, called cisregulatory elements. A long-term goal of genomics is to identify and annotate all essential elements of the genome. Most coding elements of the genome have been identified and annotated; however, most regulatory elements have not. This chapter describes a method for the high thr...
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The alleged neural basis of empathic responses to artworks is only of marginal relevance for aesthetics and for cognitive theories of art, contrary to Gallese and Freedberg [1]. The activity of the mirror neuron system (MNS) has been claimed to provide the neural underpinnings for several mental capacities, including, but not limited to, imitation, mindreading, language understanding and concep...
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Gene expression is regulated by combinations of transcription factors, which can be mapped to regulatory elements on a genome-wide scale using ChIP experiments. In a previous ChIP-chip study of USF1 and USF2 we found evidence also of binding of GABP, FOXA2 and HNF4a within the enriched regions. Here, we have applied ChIP-seq for these transcription factors and identified 3064 peaks of enrichmen...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2013
ISSN: 1471-2164
DOI: 10.1186/1471-2164-14-638