Non- 13 CO 2 targeted breath tests: a feasibility study
نویسندگان
چکیده
منابع مشابه
Non-(13)CO2 targeted breath tests: a feasibility study.
Breath tests allow a non-invasive and fast diagnostic of different specific enzymes' phenotypic functionality. Over the last decade several 13C-breath tests were successfully tested, with the (13)C-urea breath test being approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). The use of other targets than labeled (13)CO2 in exhaled breath offers additional...
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Breath tests have in common the fact the subject is given a substrate in which C atoms normally present in the functional group are replaced by the stable isotope C. This functional group is cleaved enzymatically under specific circumstances, during either transit through the gastrointestinal tract, absorption, or further metabolism of the absorbed substrate. After cleavage, the labeled subgrou...
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In gastroenterological practice, breath tests (BTs) are diagnostic tools used for indirect, non-invasive assessment of several pathophysiological metabolic processes, by monitoring the appearance in breath of a metabolite of a specific substrate. Labelled substrates originally employed radioactive carbon 14 ((14)C) and, more recently, the stable carbon 13 isotope ((13)C) has been introduced to ...
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In paediatric practice proper digestion of carbohydrates is of major importance for adequate growth and development and for prevention of intestinal complaints. Several carbohydrates can be considered in this respect: (a) lactose: the main carbohydrate in the nutrition of early life and also in later life for many white people; (b) starch: the main energy supplier in our food; (c) fructose: a c...
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ژورنال
عنوان ژورنال: Journal of Breath Research
سال: 2014
ISSN: 1752-7163
DOI: 10.1088/1752-7155/8/4/046005