Nocuous Skin Manifestations of Spironolactone: Drug Induced Leukocytoclastic Vasculitis

Warfarin-induced leukocytoclastic vasculitis.

Skin reactions associated with oral coumarin-derived anticoagulants are an uncommon occurrence. Leukocytoclastic vasculitis (LV) is primarily a cutaneous small vessel vasculitis, though systemic involvement may be encountered. We report 4 patients with late-onset LV probably due to warfarin. All 4 patients presented with skin eruptions that developed after receiving warfarin for several years. ...

Acenocoumarol-induced leukocytoclastic vasculitis.

Correspondence: F.J. Jiménez Gonzalo, M.D., Servicio de Hematología y Hemoterapia, Hospital de la Merced, Avenida de la Constitución 2, 41640 Osuna, Seville, Spain. Phone: international +34-95-5820920 – Fax: international +34-95-5820544 – E-mail: [email protected] We report a case of a acenocoumarol (Sintrom®)-induced vasculitis in a 54-year-old white female receiving oral anticoagulant ther...

Valproate-acid-induced cutaneous leukocytoclastic vasculitis.

Etiologies and prognostic factors of leukocytoclastic vasculitis with skin involvement

In this study, outcomes of patients with leukocytoclastic vasculitis (LCV) were analyzed focusing on clinical, histopathology and laboratory findings, relapses, and survival.Data from patients with cutaneous vasculitis diagnosed between January 1, 2000, and December 31, 2010, at Dijon University Hospital (France) were retrospectively reviewed. LCV was defined as perivascular neutrophilic infilt...

Dermatologic Diagnosis: Leukocytoclastic Vasculitis.

Leukocytoclastic vasculitis (LCV), also termed hypersensitivity vasculitis, is a small-vessel vasculitis. The skin is the organ most commonly involved in LCV. Typical presentation is a painful, burning rash predominantly in the lower extremities. The most common skin manifestation is palpable purpura. Other skin manifestations include maculopapular rash, bullae, papules, plaques, nodules, ulcer...