No TP63 rearrangements in a selected group of primary cutaneous CD30+ lymphoproliferative disorders with aggressive clinical course

Primary Cutaneous CD30+ T-Cell Lymphoproliferative Disorders

It is critical to distinguish CD30+ T-cell LPDs from other CD30+ processes involving the skin that include: Systemic lymphomas (eg, systemic ALCL, ATLL, PTCL), Other cutaneous process such as other CD30+ skin lymphomas such as mycosis fungoides (MF), especially transformed MF, cytotoxic T-cell lymphomas, and Benign disorders such as lymphomatoid drug reactions, arthropod bites, viral infections...

Presence of t(2;5) in primary CD30+ cutaneous lymphoproliferative disorders.

CD30+ lymphoproliferative disorders.

27. Thol F, Weissinger EM, Krauter J, Wagner K, Damm F, Wichmann F, et al. IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis. Haematologica 2010;95(10):1668-74. 28. Kosmider O, Gelsi-Boyer V, Slama L, Dreyfus F, Beyne-Rauzy O, Quesnel B, et al. Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and M...

Galectin-3 Expression in Primary Cutaneous CD30-Positive Lymphoproliferative Disorders and Transformed Mycosis Fungoides.

BACKGROUND In nodal anaplastic large cell lymphoma, strong expression of galectin-3 (Gal-3) has been found, but only very few cases of primary cutaneous lymphoma have so far been examined. OBJECTIVES To investigate 11 primary cutaneous anaplastic large cell lymphomas (PCALCL), 47 lymphomatoid papuloses (LYP) and 14 cases of transformed mycosis fungoides with CD30 expression (MF-T) for Gal-3 e...

Primary cutaneous CD30+ lymphoproliferative disorders: new insights into biology and therapy.

The spectrum of CD30+ lymphoproliferative diseases of the skin includes CD30+ cutaneous anaplastic large cell lymphoma, lymphomatoidpapulosis, as well as borderline cases. These entities constitute the second most common group of cutaneous lymphomas according to the newly revised World Health Organization and European Organisation for Research and Treatment of Cancer consensus classification. R...