No HELLP at all: Post-partum atypical hemolytic uremic syndrome treated with Eculizumab: A case report
نویسندگان
چکیده
Atypical hemolytic uremic syndrome (aHUS) is a rare condition among thrombotic microangiopathies (TMA). Pregnancy known precipitating factor of complement mediated TMA. The occurrence microangiopathic anemia, thrombocytopenia and acute kidney injury presents diagnostic therapeutic challenges. Diverse causes include hemolysis, elevated liver enzymes, low platelets (HELLP syndrome) in pregnant women. In pregnancy or postpartum, the aHUS critical complication requiring urgent diagnosis treatment. considered to be result underlying condition, with understanding that therapy focused on condition. Five documented cases pregnancy-associated treated Eculizumab have been reported, making extremely rare. We present case woman HELLP induced aHUS. patient presented evidence dysregulation system renal insufficiency. Since initiation Eculizumab, C5 inhibitor, development insufficiency diminished became dialysis independent.
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n engl j med 369;14 nejm.org october 3, 2013 1377 [CI], 0.57 to 0.83) for the first 21 days, 1.00 (95% CI, 0.57 to 1.76) for 22 to 60 days, and 0.38 (95% CI, 0.18 to 0.82) for 61 to 90 days. We also await results of trials such as POINT and TARDIS for confirmation of these results in non-Chinese populations. We agree with Jeong that there may be important differences according to the patients’ ...
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ژورنال
عنوان ژورنال: World Journal Of Advanced Research and Reviews
سال: 2022
ISSN: ['2581-9615']
DOI: https://doi.org/10.30574/wjarr.2022.15.2.0585