No eczema without keratinocyte death

No eczema without keratinocyte death.

Eczematous dermatitis comprises a heterogenous group of inflammatory skin diseases characterized by a typical morphological reaction pattern. In the acute stage, the typical clinical features include itching, redness, papules, and vesicles associated with exudation. The two most frequent reasons for an eczematous reaction are atopic dermatitis (AD) and allergic contact dermatitis (ACD). Althoug...

Death without caspases, caspases without death.

Apoptosis is a conserved cell-death process displaying characteristic morphological and molecular changes including activation of caspase proteases. Recent work challenges the accepted roles of these proteases. New investigations in mice and the nematode Caenorhabditis elegans suggest that there could be caspase-independent pathways leading to cell death. In addition, another type of cell death...

No psychiatry without psychopharmacology.

No Arbitrage without Semimartingales

We show that with suitable restrictions on allowable trading strategies, one has no arbitrage in settings where the traditional theory would admit arbitrage possibilities. In particular, price processes that are not semimartingales are possible in our setting, for example fractional Brownian motion.

No Current without Heat

We show for a large class of interacting particle systems that whenever the stationary measure is not reversible for the dynamics, then the mean entropy production in the steady state is strictly positive. This extends to the thermodynamic limit the equivalence between microscopic reversibility and zero mean entropy production: time-reversal invariance cannot be spontaneously broken.