منابع مشابه
Protein Flexibility (1): FIRST and NMA Basics
Normal mode analysis (NMA) is a standard technique for studying the dynamics of biological systems. It provides an analytic description of the dynamics in a macromolecular system near a minimum by using a harmonic approximation of the potential. NMA can be applied in the analysis of protein flexibility. It has been shown that over half of the 3800 Yale protein movements can be modelled in a str...
متن کاملElastic network models and coarse-grained NMA
The realization that experimentally observed functional motions of proteins can be predicted by coarse-grained normal mode analysis (NMA) has renewed interest in applications to structural biology. Notable applications include the prediction of biologically relevant motions for proteins and supramolecular structures driven by their structure-encoded collective dynamics; the refinement of low-re...
متن کاملTITLE An NMA - Guided Path Planning
This paper presents a new method for computing macromolecular motions based on the combination of path planning algorithms, originating from robotics research, and elastic network normal mode analysis. The low-frequency normal modes are regarded as the collective degrees of freedom of the molecule. Geometric path planning algorithms are used to explore these collective degrees of freedom in ord...
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I want, very briefly, to outline what we have been trying to do at the National Association for Mental Health to solve the problems that have arisen in Child Guidance largely as a result of the National Health Service Act. In 1944, when the Education A-ct went through, we felt that a very large part of our work had been done : Child Guidance was on the map ; it was an obligation of the Local Ed...
متن کاملDo we know the best treatment for in-stent restenosis via network meta-analysis (NMA)?: simple methods any interventionalist can use to assess NMA quality and a call for better NMA presentation.
I n this issue of JACC: Cardiovascular Interventions, Lee et al. (1) present the results of a Bayesian network meta-analysis (NMA) to assess the relative efficacy of drug-eluting stents (DES), drug-eluting balloons (DEB), and plain old balloon angioplasty (POBA) used to treat in-stent restenosis (ISR), using target lesion revascularization (TLR) as the outcome measure and 11 randomized, control...
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ژورنال
عنوان ژورنال: Journal of Nepal Medical Association
سال: 2003
ISSN: 1815-672X,0028-2715
DOI: 10.31729/jnma.1327