Nitroxyl donors for acute heart failure: promising newcomers
نویسندگان
چکیده
منابع مشابه
Nitroxyl (HNO): A novel approach for the acute treatment of heart failure.
BACKGROUND The nitroxyl (HNO) donor, Angeli's salt, exerts positive inotropic, lusitropic, and vasodilator effects in vivo that are cAMP independent. Its clinical usefulness is limited by chemical instability and cogeneration of nitrite which itself has vascular effects. Here, we report on effects of a novel, stable, pure HNO donor (CXL-1020) in isolated myoctyes and intact hearts in experiment...
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ژورنال
عنوان ژورنال: European Journal of Heart Failure
سال: 2017
ISSN: 1388-9842
DOI: 10.1002/ejhf.793