منابع مشابه
Fatal nitrofurantoin lung.
Nitrofurantoin is a drug commonly used for urinary tract infections. It acts by damaging bacterial DNA. It is given in dose of 50-100 mg orally and is generally considered a safe drug but has occasionally been known to cause pulmonary toxicity which is usually reversible and only rarely fatal. We present a case of an elderly lady receiving nitrofurantoin for her urinary tract infection who deve...
متن کاملSevere nitrofurantoin lung disease resolving without the use of steroids.
We report a case of an elderly woman who developed a severe, chronic pulmonary reaction to nitrofurantoin therapy that she had taken continuously for three years to prevent urinary tract infections. The patient was taking no other drug known to cause lung disease but the diagnosis was delayed by failure to recognize the association between nitrofurantoin and adverse drug reactions affecting the...
متن کاملNitrofurantoin-induced lung- and hepatotoxicity.
We present the case of a patient referred to the gastroenterology service for investigation of abnormal liver function tests. She had been taking nitrofurantoin for 16 months as prophylaxis against urinary tract infections. CT scan showed evidence of lung pneumonitis and low attenuation in the liver parenchyma. Nitrofurantoin-induced pneumonitis and hepatotoxicity was diagnosed. The patient res...
متن کاملUnrecognized Interstitial Lung Disease as a Result of Chronic Nitrofurantoin Use
Drug-induced interstitial lung disease is a rare condition attributed to several medications, including antimicrobial agents such as amphotericin B, anti-inflammatory agents such as methotrexate, biologic agents such as bevacizumab, and cardiovascular agents and chemotherapeutic agents. We describe the case of a 73-year-old female who developed interstitial lung disease following chronic use of...
متن کاملLung toxicity and Nitrofurantoin: the tip of the iceberg?
A 56-year-old female was referred to the respiratory clinic by her general practitioner with a 3-month history of dyspnoea and cough. She was a non-smoker. Her cough persisted despite several trials of medication, including antibiotics and inhaled bronchodilator and steroid therapy. Her past medical history included cervical cancer in 1997 with vault relapse in 1999, treated by hysterectomy, ch...
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ژورنال
عنوان ژورنال: American Journal of Roentgenology
سال: 1969
ISSN: 0361-803X,1546-3141
DOI: 10.2214/ajr.107.4.818