Nitrofurantoin-Induced Pulmonary Toxicity: Always Review the Medication List

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Nitrofurantoin‐induced acute pulmonary toxicity

We report a case of a female admitted to the emergency department with fever and severe type I acute respiratory failure. After detailed examination, all other potential causes were excluded and the patient was diagnosed with nitrofurantoin-induced acute pulmonary toxicity.

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Fatal Nitrofurantoin-Induced Pulmonary Toxicity: A Potentially Preventable Medical Error

The majority of patients affected with nitrofurantoin pulmonary toxicity are elderly women [1]. The proposed mechanism of toxicity is either idiosyncratic oxydant-mediated tissue injury by nitrofurantoin metabolites causing depletion of cellular glutathione (chronic form) or by immunological response induced by nitrofurantoin metabolites acting as heptanes and resulting a hypersensitivity react...

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Nitrofurantoin-induced pulmonary toxicity: A case report and review of the literature.

This paper describes a case of lung injury attributed to the use of Nitrofurantoin and a review of the relevant literature. An 88-year-old woman was admitted to the floor for the evaluation of recent symptoms of dyspnea, fatigue and productive cough. She was initiated on nitrofurantoin 300 mg per day for the treatment of a urinary tract infection 3 days earlier. Upon examination, chest ausculta...

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Nitrofurantoin-induced pulmonary fibrosis: a case report

INTRODUCTION Nitrofurantoin is a commonly used drug in the treatment and prevention of urinary tract infections. Many adverse effects of nitrofurantoin have been documented, including aplastic anemia, polyneuritis, and liver and pulmonary toxicity. CASE PRESENTATION We describe the clinical history and the autopsy findings in a 51-year-old woman with lung fibrosis of unknown etiology. She had...

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Nitrofurantoin-induced pulmonary reaction involving respiratory symptoms: case report.

Nitrofurantoin is an antimicrobial agent that is commonly used to treat urinary tract infections. It may also be used prophylactically for patients with recurrent urinary tract infection. Several cases and various clinical manifestations of pulmonary reactions to nitrofurantoin have been described in the literature. Early recognition of such reactions may prevent disability and death. This arti...

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ژورنال

عنوان ژورنال: Cureus

سال: 2020

ISSN: 2168-8184

DOI: 10.7759/cureus.9807