Nitric Oxide Scavenger Carboxy-PTIO Impaired Memory of Avoidance Conditioning in Goldfish
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منابع مشابه
Nitric Oxide Scavenger Carboxy-PTIO Impaired Memory of Avoidance Conditioning in Goldfish
The long-term potentiation (LTP), an activity-induced increase in the efficacy of neurotransmission, has long been conceived to be a physiological correlate of learning and memory. Investigations of synaptic transmission suggest that the postsynaptic N-methyl-D-aspartate (NMDA) receptor is the upstream mediator of LTP, while nitric oxide (NO), a retrograde messenger from postsynaptic neurons to...
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Recent studies have indicated that nitric oxide may play a role in inhalation anaesthesia. Inhibition of nitric oxide synthase reduces the minimum alveolar concentration (MAC) for inhalation anaesthetics and decreases cerebellar nitric oxide synthase (NOS) activity in rats. In this study, we have explored further the role of nitric oxide in isoflurane anaesthesia by examining the effects of a n...
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Nitronyl nitroxides, such as derivatives of 2-phenyl4,4,5,5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIOs), react with NO to form the corresponding imino nitroxides (PTIs) and NO2. PTIOs are considered as monitors of NO, stoichiometric sources of NO2, biochemical and physiological effectors, specific tools for the elimination of NO, and potential therapeutic agents. However, a better understand...
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Abstract: Introduction: Nitric oxide (NO) is a retrograde messenger in hippocampal synaptic plasticity which involves in learning and memory processes. Previous studies revealed that hippocampal pyramidal cells contain NO synthase (NOS) enzyme which produce NO and could be a promising target to evaluate the role of NO in brain cognitive functions. So in this study, using NOS inhibitor (L-NAME)...
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The shuttlebox performance of goldfish was studied under standardized conditions in a variety of problems--with or without an avoidance contingency, a conditioned stimulus (CS)-termination contingency, and an escape contingency. The effects of CS-only, unconditioned stimulus (US)-only, and explicitly unpaired training were also examined. All the data could be simulated quantitatively with a ver...
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ژورنال
عنوان ژورنال: Open Journal of Social Sciences
سال: 2014
ISSN: 2327-5952,2327-5960
DOI: 10.4236/jss.2014.25017