Niosomes as Nanoparticular Drug Carriers: Fundamentals and Recent Applications

An Overview on Niosomes as Efficient Drug Carriers

Over the past years the treatments of disease have undergone a revolutionary change. With the advancement of pharmaceutical science not only novel drug delivery system have been developed but also emphasis has been laid to deliver the active constituent to the diseased site.The basic component of such a system is a suitable carrier that protects the active medicament from degradation or clearan...

Iron oxide-doped niosomes as drug carriers for magnetically targeted drug delivery

Magnetism has wide applications in various fields, such as diagnostics, drug targeting, molecular biology, cell isolation, cell purification, hyperthermia, and radioimmunoassay. In this study, we synthesized niosomes doped with iron oxide nanoparticles and a fluorophore for potential applications in magnetically targeted drug delivery. Release kinetics of the fluorophore and cytotoxicity were a...

Niosomes as vesicular carriers for delivery of proteins and biologicals

meenakshikanwar(at)yahoo.com Abstract Over the past several years, treatment of infectious diseases and immunization has undergone a paradigm shift. Stemming from the nanobiotechnology research, not only a large number of disease-specific biologicals have been developed, but also enormous efforts have been made to effectively deliver these biologicals. Niosomes are vesicular systems prepared fr...

Niosomes as Carrier in Dermal Drug Delivery

Novel PEG-coated niosomes based on bola-surfactant as drug carriers for 5-fluorouracil.

Innovative niosomes made up of α,ω-hexadecyl-bis-(1-aza-18-crown-6) (bola), Span 80® and cholesterol (2:5:2 molar ratio) are proposed as suitable delivery systems for the administration of 5-fluorouracil (5-FU), an antitumoral compound largely used in the treatment of breast cancer. The bola-niosomes, after sonication procedure, showed mean sizes of ~200 nm and a loading capacity of ~40% with r...