منابع مشابه
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Atherosclerosis is the product of excessive lipid accumulation and inflammation in the artery wall. The lipid that tops every list of suspects is cholesterol, which is the primary lipid in low-density lipoproteins (LDL). Cholesterol exists either as a simple molecule or as cholesterol esters, in which the hydroxyl group is linked to a fatty acyl moiety. In cells, cholesterol esters are synthesi...
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The cylindromatous gene Cyld encodes a deubiquitylase (DUB), which regulates NF-jB activation. CYLD deficiency results in faulty innate and adaptive immune systems in mice, the basis for which remains incompletely understood. In this issue of The EMBO Journal, Sun and colleagues report that CYLD-deficient mice develop the innatelike lymphocyte called natural killer T (NKT) cells but lose them t...
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Cosmic-ray astrophysics has advanced rapidly in recent years, and its impact on other astronomical disciplines has broadened. Many new experiments measuring these particles, both directly in the atmosphere or space and indirectly via γ rays and synchrotron radiation, have widened the range and quality of the information available on their origin, propagation, and interactions. The impact of low...
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The division of labor among two types of T helper (Th) subsets, first described over 20 yr ago, has been buffeted by the discovery of new subsets and new cytokines that can be coaxed out of T cells with increasing disregard for the subset of origin. Although Th17 cells and regulatory T (T reg) cells are widely accepted subsets, and others are being proposed, their plasticity is difficult to rec...
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Prenatal screening for Down syndrome affects millions of pregnancies every year worldwide. The vast majority of screen-positive results are false, yet encourage invasive diagnostic procedures that pose additional risks to unborn babies. As a direct consequence many babies who do not have Down syndrome are lost. We estimate that current screening practice in England and Wales reduces annual live...
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ژورنال
عنوان ژورنال: Environmental Humanities
سال: 2020
ISSN: 2201-1919,2201-1919
DOI: 10.1215/22011919-8142396