NFATc3-Induced Reductions in Voltage-Gated K + Currents After Myocardial Infarction
نویسندگان
چکیده
منابع مشابه
NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction.
Reductions in voltage-activated K+ (Kv) currents may underlie arrhythmias after myocardial infarction (MI). We investigated the role of beta-adrenergic signaling and the calcineurin/NFAT pathway in mediating the reductions in Kv currents observed after MI in mouse ventricular myocytes. Kv currents were produced by the summation of 3 distinct currents: I(to), I(Kslow1), and I(Kslow2). At 48 hour...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2004
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000128406.08418.34