NF90 regulation of immune factor expression in response to malaria antigens

Humoral Immune Response of Cultured Persian Sturgeon (Acipenser persicus) to Four Different Aeromonas hydrophila Antigens

Cationic Immune Stimulating Complexes Containing Soluble Leishmania Antigens: Preparation, Characterization and in Vivo Immune Response Evaluation

Background: Cationic immune stimulating complexes (PLUSCOMs) are particulate antigen delivery systems. PLUSCOMs consist of cationic immunostimulatory complexes (ISCOMs) derivatives and are able to elicit in vivo T cell responses against an antigen. Objective: To evaluate the effects of PLUSCOMs containing Leishmaniamajor antigens (SLA) on the type of immune response generated in the murine mod...

Immune Response in Malaria

M ALARIA IS ONE of the major parasitic diseases affecting humans today, contributing greatly to the high mortality rates in the developing world. The original epidemiologic concept of “malaria eradication” for large endemic areas, introduced by the World Health Organization (WHO) in the 1960s, has now been replaced by the concept of “control,” given the increase in the morbidity and mortality r...

Immune Response Regulation by Leishmania Secreted and Nonsecreted Antigens

Leishmania infection consists in two sequential events, the host cell colonization followed by the proliferation/dissemination of the parasite. In this review, we discuss the importance of two distinct sets of molecules, the secreted and/or surface and the nonsecreted antigens. The importance of the immune response against secreted and surface antigens is noted in the establishment of the infec...

Immune response to mutant neo-antigens

Extending observations on the immunogenicity of neo-antigens that arise in the course of oncogenesis and tumor progression, we suggest that somatic mutations affecting normal tissues also lead to generation of new epitopes. We hypothesize that, at least under inflammatory conditions, immune responses against such neo-antigens may lead to the elimination or functional impairment of normal cells,...