Next‐Generation D 2 ‐Symmetric Chiral Porphyrins for Cobalt(II)‐Based Metalloradical Catalysis: Catalyst Engineering by Distal Bridging

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Metalloradical activation of α-formyldiazoacetates for the catalytic asymmetric radical cyclopropanation of alkenes† †Electronic supplementary information (ESI) available. CCDC 1532256. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc00658f Click here for additional data file. Click here for additional data file.

For the first time, a-formyldiazoacetates have been successfully applied for the asymmetric cyclopropanation of alkenes via Co(II)-based metalloradical catalysis. The cobalt(II) complex of the D2symmetric chiral amidoporphyrin [Co(3,5-DiBu-ChenPhyrin)] is an effective metalloradical catalyst that can activate a-formyldiazoacetates to cyclopropanate both aromatic and aliphatic olefins with varie...

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ژورنال

عنوان ژورنال: Angewandte Chemie International Edition

سال: 2019

ISSN: 1433-7851,1521-3773

DOI: 10.1002/anie.201812379