Newer protocols and future in collagen cross-linking

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collagen cross-linking

patients with keratoconus constitute a large proportion of patients suffering from anterior segment disorders. as of this time, however, its pathogenesis has not yet been elucidated. a reduction in cross-link between collagen molecules has been observed in keratoconic eyes as compared to normal ones. present approaches only address refractive errors resulting from the abnormal abnormal corneal ...

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Collagen Cross-Linking: Current Status and Future Directions

Collagen cross-linking (CXL) using UVA light and riboflavin (vitamin B2) was introduced as a clinical application to stabilize the cornea by inducing cross-links within and between collagen fibers. CXL has been investigated extensively and has been shown clinically to arrest the progression of keratoconic or post-LASIK ectasia. With its minimal cost, simplicity, and proven positive clinical out...

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Histopathological Finding of Cornea after Collagen Cross-Linking Using Riboflavin and Ultraviolet A in Rabbit

Purpose: To evaluate the histopathological changes of the cornea in rabbit corneas after accelerated collagen cross-linking. Methods: Right eyes of 7 adult New Zealand albino rabbits weighing 1.5 to 2.0 kg were studied. Right eyes of all animals were in the treatment group and left eyes were in the control group. The epithelium of all right eyes was removed and was crossed-linked with riboflavi...

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Comparative Study of the Effect of Indomethacin and Acetaminophen on Pain after Collagen Cross-Linking Surgery

Introduction: One of the surgeries that needs to be considered after pain and discomfort is corneal cross-linking of the cornea. The aim of this study was to compare the effect of indomethacin and acetaminophen oral surgery before surgery on postoperative pain in the patients undergoing collagen cross-linking surgery. Methods: The present study was a double-blind clinical trial study that was ...

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Standard versus trans-epithelial collagen cross-linking in keratoconus patients suitable for standard collagen cross-linking

PURPOSE Evaluating the clinical results of trans-epithelial collagen cross-linking (CXL) and standard CXL in patients with progressive keratoconus. METHODS This prospective study comprised 20 eyes of 20 patients with progressive keratoconus. Ten eyes were treated by standard CXL and ten by trans-epithelial cross-linking (TE-CXL, epithelium on) with 1 year of follow-up. All patients underwent ...

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ژورنال

عنوان ژورنال: Indian Journal of Ophthalmology

سال: 2013

ISSN: 0301-4738

DOI: 10.4103/0301-4738.116076