Newcastle disease virus, rituximab, and doxorubicin combination as anti-hematological malignancy therapy
نویسندگان
چکیده
منابع مشابه
Newcastle disease virus, rituximab, and doxorubicin combination as anti-hematological malignancy therapy
Hematological malignancies are important diseases that need more powerful therapeutics. Even with current targeting therapies, such as rituximab and other chemotherapeutic agents, there is a need to develop new treatment strategies. Combination therapy seems the best option to target the tumor cells by different mechanisms. Virotherapy is a very promising treatment modality, as it is selective,...
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Newcastle disease virus (NDV) is one of the most economically important avian virus which affects the poultry industry worldwide. Although NDV is being very actively studied in Malaysia, there are still no studies on its potential as an anticancer agent, a new approach to treating cancer known as virotherapy. Currently, a collaborative research is being undertaken between Universiti Putra Malay...
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Infection of L cells with Newcastle disease virus (NDV) results in abortive replication, with the production of very few plaque-forming units (PFU) of virus per cell (W. C. Wilcox, Virology 9:30, 1959; K. Paucker et al., Virology 17:301, 1962). It is known that interferon is synthesized by L cells infected with NDV, and the possibility exists that this endogenously produced inhibitor may be res...
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ژورنال
عنوان ژورنال: Oncolytic Virotherapy
سال: 2016
ISSN: 2253-1572
DOI: 10.2147/ov.s95250