منابع مشابه
New trends in articular cartilage repair
Damage to the articular cartilage is an important, prevalent, and unsolved clinical issue for the orthopaedic surgeon. This review summarizes innovative basic research approaches that may improve the current understanding of cartilage repair processes and lead to novel therapeutic options. In this regard, new aspects of cartilage tissue engineering with a focus on the choice of the best-suited ...
متن کاملNew Horizons in Articular Cartilage Repair
Articular cartilage rarely reforms a functional hyaline surface after injury. Most simple cartilage lacerative injuries reach a benign nonhealing phase, which remains unchanged over time. Deeper cartilage lesions, which violate the tide-mark and extend into the subchondral bone plate, result in an improved healing response. This is largely because of the proliferation of undifferentiated mesenc...
متن کاملArticular Cartilage Repair
This review traces the genealogy of the field of articular cartilage repair from its earliest attempts to its present day vast proliferation of research advances. Prior to the 1980s there was only sporadic efforts to regenerate articular cartilage as it was considered to be incapable of regeneration based on historical dogma. The first flurry of reports documented the use of various cell types ...
متن کاملArticular Cartilage: Structure, Composition, Injuries and Repair
Articular cartilage has a unique structure that makes it very different from any other tissues in the body. It has such specific roles and functions such as weight bearing with low frictional coefficient that the main bulk of its structure is based on that alone, thus making it a vascular, and thereby greatly limiting its self regeneration capabilities. This article aims to review the structure...
متن کاملCurrent strategies for articular cartilage repair.
Defects of articular cartilage that do not penetrate to the subchondral bone fail to heal spontaneously. Defects that penetrate to the subchondral bone elicit an intrinsic repair response that yields a fibrocartilaginous repair tissue which is a poor substitute for hyaline articular cartilage. Many arthroscopic repair strategies employed utilise this intrinsic repair response to induce the form...
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ژورنال
عنوان ژورنال: Journal of Experimental Orthopaedics
سال: 2015
ISSN: 2197-1153
DOI: 10.1186/s40634-015-0026-0