New Oral Anticoagulants for Stroke Prevention in Atrial Fibrillation: More Choices Bring More Challenges
نویسندگان
چکیده
منابع مشابه
New oral anticoagulants for stroke prevention in atrial fibrillation: more choices bring more challenges.
For patients with atrial fibrillation, anticoagulant therapy is essential to reduce the risk of ischemic stroke that is associated with this arrhythmia. Historically, warfarin has been the preferred treatment for patients at moderate to high risk despite many potential limitations. With the development of newer oral anticoagulants, clinicians now have 3 additional options: dabigatran, rivaroxab...
متن کاملAdjusted indirect comparison of new oral anticoagulants for stroke prevention in atrial fibrillation.
BACKGROUND Vit-K antagonists are the therapy of choice to prevent thromboembolic events due to atrial fibrillation since many years. New oral anticoagulants (NOA) showed encouraging results vs. warfarin but there are no data directly comparing different NOA. We performed an adjusted indirect meta-analysis. METHODS Randomized controlled trials (RCTs) were searched. Efficacy end points were the...
متن کاملEarly Experience of New Oral Anticoagulants for Stroke Prevention in Octogenarian Patients with Atrial Fibrillation
Background and Objectives: The safety of new oral anticoagulants (NOACs) depends largely on renal function. As renal function deteriorates with aging, the safety of NOACs is clinically important for very old cardiac patients. This study analyzed the efficacy and safety of NOACs prescribed to an octogenarian population in a university hospital. Subject and Methods: A total of 158 consecutive pat...
متن کاملNew oral anticoagulants for atrial fibrillation.
Case 1A: A 68-year-old man with a past medical history of atrial fibrillation (AF), hypertension, and type 2 diabetes mellitus has been on anticoagulation therapy with warfarin for 6 years. The patient’s target international normalized ratio (INR) is 2.0 to 3.0. The patient has been managed by a pharmacist-run anticoagulation clinic, and his recent warfarin doses and INR values are shown in Tab...
متن کاملNew Oral Anticoagulants for Atrial Fibrillation
ABSTRACT Atrial fibrillation (AF) is the most common cardiac arrhythmia in the U.S. Anticoagulation is recommended for stroke prevention in AF patients with intermediate-to-high stroke risk (i.e., patients with a CHADS2 score of 1 or greater). Warfarin was previously the only option for oral anticoagulation in these patients, but three new oral anticoagulants have become available as alternativ...
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ژورنال
عنوان ژورنال: Hospital Pharmacy
سال: 2013
ISSN: 0018-5787,1945-1253
DOI: 10.1310/hpj4805-366