New mutants of Neurospora crassa highly resistant to the microtubule inhibitor benomyl
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منابع مشابه
Isolation and properties of selenomethionine-resistant mutants of Neurospora crassa.
Mutants resistant to selenomethionine were isolated, and their properties studied. Mapping studies indicate that the mutation sites are located near the eth-1(r) locus in linkage group I, about ten map units away from the mating type locus. The sites of new mutation are either allelic to or very close to eth-1(r). They are resistant not only to selenomethionine but also to ethionine, while the ...
متن کاملMutants of NEUROSPORA CRASSA Permeable to Histidinol.
I N Neurospora, L-histidinol is the immediate precursor of L-histidine, as shown by the isolation of L-histidinol dehydrogenase and the study of its catalytic functions (AMES 1957; CREASER, BENNETT and DRYSDALE 1965). The failure of histidine mutants, with the histidinol dehydrogenase function intact, to grow on histidinol, suggests that histidinol cannot enter the cell. However, CATCHESIDE ( 1...
متن کاملA survey of new morphological mutants in Neurospora crassa.
HIS investigation of morphological mutants in Neurospora crassa was underTtaken to examine a wide spectrum of such strains and to obtain information regarding their number and distribution in each of the seven linkage groups. This information, as well as a comparative study of their morphological characteristics, is important both theoretically and practically in facilitating further investigat...
متن کاملUltraviolet-sensitive mutants in Neurospora crassa.
ADIATION-SENSITIVE mutants in bacteria have been reported repeatedly in recent years (s,ee SETLOW 1966). Several loci concerned with sensitivity have been mapped. Some of these mutants not only lacked the ability to repair damaged DNA but also failed to undergo genetic recombination (CLARK and MARGULIES 1965; HOWARD-FLANDERS and THERIOT 1966; VAN DE PUTTE et al. 1966). Among the eucaryotic orga...
متن کاملMutants affecting thymidine metabolism in Neurospora crassa.
When (14)C-thymidine labeled only in the ring is administered to Neurospora crassa, the majority of the recovered label is found in the ribonucleic acid (RNA). Three mutants were isolated in which different steps are blocked in the pathway that converts the pyrimidine ring of thymidine to an RNA precursor. Evidence from genetic, nutritional, and accumulation studies with the three mutants shows...
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ژورنال
عنوان ژورنال: Fungal Genetics Reports
سال: 1997
ISSN: 1941-4765
DOI: 10.4148/1941-4765.1288