New In Situ Catalysts Based on Nitro Functional Pyrazole Derivatives and Copper (II) Salts for Promoting Oxidation of Catechol to o-Quinone

Herein, new substituted ligands based on pyrazole (L1–L4) were synthesized via a one-step by condensing (1H-pyrazole-1-yl) methanol with different primary amine compounds. The present work utilized the catalytic properties of in situ complexes formed these various copper (II) salts viz. Cu(CH3COO)2, CuSO4, CuCl2, and Cu(NO3)2 for oxidation catechol to o-quinone. studies showed that activities depend nature concentration ligand, counterion, solvent. It was observed complex L2 Cu(CH3COO)2 exhibited good activity Vmax 41.67 µmol L−1 min−1 Km 0.02 mol L−1.