New clinical diagnostic criteria for allergic bronchopulmonary aspergillosis/mycosis and its validation

BackgroundThere are several clinical diagnostic criteria for allergic bronchopulmonary aspergillosis (ABPA). However, these have not been validated in detail, and no mycosis (ABPM) currently available.ObjectiveThis study proposes new ABPA/ABPM, consisting of 10 components, compares its sensitivity specificity to existing methods.MethodsRosenberg-Patterson proposed 1977, the International Society Human Animal Mycology (ISHAM) 2013, this were applied 79 cases with pathological ABPM control population mucin absence fungal hyphae (n = 37), chronic eosinophilic pneumonia 64), Aspergillus-sensitized severe asthma 26), or pulmonary 24). These also 179 physician-diagnosed ABPA/ABPM a nationwide Japanese survey.ResultsThe Rosenberg-Patterson criteria, ISHAM 25.3%, 77.2%, 96.2%, respectively. The 49.2%, 82.7%, 94.4%, areas under curve receiver-operating characteristic curves 0.85, 0.90, 0.98, that culture-positive non-Aspergillus fungi 13.0%, 47.8%, 91.3%, respectively.ConclusionsThe compared showed better diagnosing ABPA/ABPM. There available. This methods. survey.