New Books April 2004
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New Books April 2004
Background: Two distinct classes of regulators have been implicated in regulating neuronal gene expression and mediating neuronal identity: transcription factors such as REST/NRSF (RE1 silencing transcription factor) and CREB (cAMP response element-binding protein), and microRNAs (miRNAs). How these two classes of regulators act together to mediate neuronal gene expression is unclear. Results: ...
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The objective of this work is to compare the adherence to therapy of patients receiving etanercept and infliximab during first tumour necrosis factor (TNF)-blocking treatment course in rheumatoid arthritis. Special emphasis is placed on potential predictors for treatment termination and the impact of concomitant methotrexate (MTX) or other disease-modifying antirheumatic drugs (DMARDs). Patient...
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Recent studies using geological and molecular phylogenetic evidence suggest several alternative evolutionary scenarios for the origin of photosynthesis. The earliest photosynthetic group is variously thought to be heliobacteria, proteobacteria or a precursor of cyanobacteria, organisms whose photosynthetic pigments make them different colors. Published: 3 January 2007 Genome Biology 2006, 7:245...
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Polymyxin B and polymyxin E (colistin) are the two polymyxins used in clinical practice. Colistin is a polymyxin-type antibiotic, disrupting the structure of Gram-negative organisms’ cell membranes, rarely used parenterally because it has nephrotoxic side effects. The polymyxins are active against selected Gram-negative bacteria, including Acinetobacter species, Pseudomonas aeruginosa, Klebsiel...
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The answer to the ethical question “How should we live?” depends in part on what we know. Years ago, Aldo Leopold called for a “land ethic” as a consequence of understanding the interdependence of individuals in a larger ecological system. Here Jessica Pierce and Andrew Jameton examine new ways of thinking about bioethics, with a sense of urgency because of current ecologic realities. They ask ...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2004
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.112-a316