Nevus Anemicus and Bier Spots in Tuberous Sclerosis Complex

Nevus Flammeus in Tuberous Sclerosis

Hypoalbuminemia in the absence of hepatic, renal, and nutritional deficiency may indicate protein malabsorption or protein losing gastroenteropathy. Abuse of laxatives like castor oil can cause protein losing gastroenteropathy(l). Castor oil is hydrolyzed in the intestine by pancreatic lipase to glycerol and ricinoleic acid. Ricinoleic acid acts as a mild irritant and causes purgation. It is al...

Bier spots.

The tuberous sclerosis complex.

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that results from mutations in the TSC1 or TSC2 genes and is associated with hamartoma formation in multiple organ systems. The neurological manifestations of TSC are particularly challenging and include infantile spasms, intractable epilepsy, cognitive disabilities, and autism. Progress over the past 15 years has demonstrated t...

Tuberous sclerosis complex.

Contrast enhanced computed tomography revealed a large well-circumscribed heterogenous retroperitoneal mass measuring 25 × 20 cm arising from the left kidney with predominant fat attenuation. Multiple smaller lesions were seen in the opposite kidney. Features were suggestive of diffuse angiomyolipomatosis of the kidneys. Hypodense lesions were also seen involving the lungslymphangioleiomyomatos...

Tuberous Sclerosis Complex in Autism

OBJECTIVE To study the prevalence rate of tuberous sclerosis complex in autistic disorder. METHODS We studied one cohort of children followed up since 2005 until 2009, with autistic disorder, to determine the incidence of tuberous sclerosis complex. We established an autistic disorder registry in 2005 at China Rehabilitation Research Center. During the 4-year period (2005-2009), we collected ...