منابع مشابه
Protein structures by spallation neutron crystallography
The Protein Crystallography Station at Los Alamos Neutron Science Center is a high-performance beamline that forms the core of a capability for neutron macromolecular structure and function determination. This capability also includes the Macromolecular Neutron Crystallography (MNC) consortium between Los Alamos (LANL) and Lawrence Berkeley National Laboratories for developing computational too...
متن کاملHydrogen bonds of DsrD protein revealed by neutron crystallography
The features of hydrogen bonds in DsrD protein from sulfate-reducing bacteria have been investigated by neutron protein crystallography. The function of DsrD has not yet been elucidated clearly, but its X-ray crystal structure revealed that it comprises a winged-helix motif and shows the highest structural homology to the DNA-binding proteins. Since any neutron structure of a DNA recognition pr...
متن کاملNeutron protein crystallography: beyond the folding structure of biological macromolecules.
Neutron diffraction provides an experimental method of directly locating H atoms in proteins, a technique complementary to ultra-high-resolution X-ray diffraction. Three different types of neutron diffractometers for biological macromolecules have been constructed in Japan, France and the USA, and they have been used to determine the crystal structures of proteins up to resolution limits of 1.5...
متن کاملNeutron Protein Crystallography. Hydrogen- and Hydration-sensitive Structural Biology
Neutron protein crystallography (NPC) has not substantially contributed to the determination of the folding structures of biological macromolecules. It takes the next step beyond the folding structure of proteins. This paper demonstrates how hydrogen atoms can be seen by NPC and how NPC can explore protonation and deprotonation of amino acid residues, hydration structures, and hydrogen-to-deute...
متن کاملFifteen years of the Protein Crystallography Station: the coming of age of macromolecular neutron crystallography
The Protein Crystallography Station (PCS), located at the Los Alamos Neutron Scattering Center (LANSCE), was the first macromolecular crystallography beamline to be built at a spallation neutron source. Following testing and commissioning, the PCS user program was funded by the Biology and Environmental Research program of the Department of Energy Office of Science (DOE-OBER) for 13 years (2002...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Kessho Gakkaishi
سال: 1996
ISSN: 0369-4585,1884-5576
DOI: 10.5940/jcrsj.38.95