Neurotrophic keratitis secondary to cerebral malformation

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[Neurotrophic keratitis].

Neurotrophic keratitis is a degenerative disease of the cornea caused by reduced corneal innervation. Trauma, tumors, inflammatory lesions and surgical procedures can damage the first branch of the trigeminal nerve on its entire course from brainstem to and within the cornea. Loss or reduction of corneal innervation leads to a reduced aqueous phase of the tear film and due to reduced supply wit...

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Neurotrophic Keratitis

Neurotrophic keratitis (NK) is a rare degenerative corneal disease that occurs as a result of partial or total impairment of trigeminal innervations, leading to a reduction (hypoesthesia) in or loss (anaesthesia) of corneal sensitivity. The impairment of sensory innervation causes a reduction in the lacrimation reflex and the vitality, metabolism and mitosis of epithelial cells, with subsequent...

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Sudden Bilateral Sensorineural Hearing Loss Secondary to Cerebral Venous Thrombosis

Introduction: Sudden sensorineural hearing loss (SSNHL) is an important otological emergency. Up to 90% of the cases are idiopathic. Cerebral venous thrombosis (CVT) is an extremely rare identifiable cause as it only represents 0.5% of all strokes.   Case Report: In this paper, an unusual case of bilateral SSNHL secondary to bilateral CVT with rapid and complete recovery is reported. The patie...

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Unilateral Punctate Keratitis Secondary to Wallenberg Syndrome

We studied three patients who developed left unilateral punctate keratitis after suffering left-sided Wallenberg Syndrome. A complex evolution occurred in two of them. In all cases, neurophysiological studies showed damage in the trigeminal sensory component at the bulbar level. Corneal involvement secondary to Wallenberg syndrome is a rare cause of unilateral superficial punctate keratitis. Th...

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Semaphorin 7a in Herpetic Neurotrophic Keratitis.

Recurrent infection of the ocular surface by herpes simplex virus type I (HSV-1), a neurotropic herpesvirus, is a leading infectious cause of corneal blindness in developed countries. The origin of recurrent infections lies in the fact that the virus establishes latency in sensory neurons of the trigeminal ganglion (TG). While the latent infection of TG is marked by the loss of viral protein sy...

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ژورنال

عنوان ژورنال: Neurología (English Edition)

سال: 2017

ISSN: 2173-5808

DOI: 10.1016/j.nrleng.2015.03.013