NEUROPSYCHIATRIC FINDINGS IN PATIENTS EXPOSED TO POLYBROMINATED BIPHENYLS

Neuropsychiatric findings in patients exposed to polybrominated biphenyls.

The inadvertent mixing of polybrominated biphenyls (PBBs) into animal feed in 1973 resulted in the contamination of thousands of Michigan farms. Farm animals who ingested this feed suffered various consequences including weight loss, decreased productivity, frequent infections, skin changes, and reproductive abnormalities.' This error was not initially known, and widespread contamination of hum...

Breast-feeding among women exposed to polybrominated biphenyls in Michigan.

In the early 1970s, the largest industrial accident in the United States resulted in widespread contamination of the food supply in Michigan with polybrominated biphenyls (PBBs). The chemical similarity of PBBs to compounds implicated as endocrine disruptors has raised the question of whether PBBs could affect the reproductive system. In the present analysis we examine the relation between seru...

Immunological studies in cattle exposed to polybrominated biphenyls

The intactness of the immune system in cattle exposed to polybrominated biphenyls (PBBs) has been investigated by using several immunoassays. Eighty-seven animals have been studied, 35 control animals (not exposed to PBBs) and 52 animals exposed to PBBs (0.02-30 ppm/g fat equivalent). The immunoassays included a complete blood count, identification of peripheral blood T and B lymphocyte subpopu...

Cohort study of Michigan residents exposed to polybrominated biphenyls: epidemiologic and immunologic findings.

Polybrominated biphenyls (PBB) were dispersed widely in Michigan by a 1973 shipping accident in which PBB was introduced into cattle feed. Human exposure resulted principally from ingestion of contaminated dairy food products. To determine whether PBB exposure has or will cause acute or chronic illness, a prospective cohort study of 4545 persons has been undertaken. Three exposure groups were s...

Polybrominated biphenyls 74 Hazard assessment of Polybrominated biphenyls