Neuropsychiatric Burden in Huntington’s Disease

Neuropsychiatric Burden in Huntington’s Disease

Huntington's disease is a disorder that results in motor, cognitive, and psychiatric problems. The symptoms often take different forms and the presence of disturbances of the psychic sphere reduces patients' autonomy and quality of life, also impacting patients' social life. It is estimated that a prevalence between 33% and 76% of the main psychiatric syndromes may arise in different phases of ...

Applying Bioinfomatics Strategies in Huntingtons Disease Research

Psychiatric onset Alexander disease: an important challenge in neuropsychiatric diagnosis

Introduction: Alexander disease is a heterogenous group of diseases with various manifestations based on age of disease onset. This rare leukodystrophy syndrome with mutations in GFAP Gene could present with developmental delay and seizure in infantile form to ataxia and bulbar palsy in adulthood. However psychiatric symptoms are not well-defined and usually evaluate after disease diagnosis not...

MRI Tz Hypointensities in basal ganglia of premanifest Huntingtons disease

Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer’s disease

AIMS Patients with Alzheimer's disease need assistance and supervision of their daily activities. They survive for protracted periods of time, placing an extensive burden of care on the caregiver prior to the patient's death. The present study addressed the predictive value of behavior-related burden on Alzheimer's disease caregivers. PARTICIPANTS 82 patients with probable Alzheimer's (73.7 +...