Neuropharmacological activities of Taxus wallichiana bark in Swiss albino mice

Anticonvulsant, analgesic and antipyretic activities of Taxus wallichiana Zucc.

Taxus wallichiana Zucc. (Himalayan Yew) is often used in northern areas of Pakistan for the treatment of pyrexia, acute pains and epilepsy. We have investigated certain pharmacological activities of the methanol leaf extract against convulsion, nociception and pyrexia induced in rodents. The aim was to justify and explore its folk uses in these pathological conditions, on scientific basis. The ...

Analgesic and neuropharmacological activities of the ethanolic extract of leaves of Kalanchoe pinnata (Lam.)Pers. in Swiss Albino mice

Inhibition of Ehrlich ascites carcinoma by Manilkara zapota L. stem bark in Swiss albino mice.

OBJECTIVE To evaluate the antitumor activity of Manilkara zapota (M. zapota) L. stem bark against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. METHODS The in vivo antitumour activity of the ethyl acetate extract of stem bark of M. zapota L. (EASM) was evaluated at 50, 100 and 200 mg/kg bw against EAC using mean survival time. After administration of the extract of M. zapota, viable E...

Radioprotective Efficacy of Lutein in Ameliorating Electron Beam Radiation-induced Oxidative Injury in Swiss Albino Mice

Background: Lutein, a carotenoid compound, has previously been studied for its antioxidant and medicinal properties as well as the moderate protection it confers against gamma radiation. This study aimed at evaluating the effects of lutein against radiation-induced hematological and biochemical changes in mice.Methods: The optimized dose of the compound was orally administered for 15 days, and ...

Antibacterial, antifungal, insecticidal, cytotoxic and phytotoxic activities of the crude extracts of Taxus wallichiana Zucc twigs

This study was proposed to investigate the in-vitro antifungal, antibacterial, insecticidal, cytotoxic and phytotoxic potential of ethanolic extract of twigs of Taxus wallichiana Zucc. Traditionally, this plant is used in folk medicines in Pakistan, for the treatment of various microbial infections. The crude sub fractions of ethanolic extracts of the plant were tested against six bacterial and...