Neuropathological changes in the brain of pigs with acute liver failure
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چکیده
منابع مشابه
Neuropathological changes in the brain of pigs with acute liver failure.
OBJECTIVE Cerebral edema is a serious complication of acute liver failure (ALF), which may lead to intracranial hypertension and death. An accepted tenet has been that the blood-brain barrier is intact and that brain edema is primarily caused by a cytotoxic etiology due to hyperammonemia. However, the neuropathological changes in ALF have been poorly studied. Using a well characterized porcine ...
متن کاملAssociation of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure.
UNLABELLED We previously demonstrated in pigs with acute liver failure (ALF) that albumin dialysis using the molecular adsorbents recirculating system (MARS) attenuated a rise in intracranial pressure (ICP). This was independent of changes in arterial ammonia, cerebral blood flow and inflammation, allowing alternative hypotheses to be tested. The aims of the present study were to determine whet...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Gastroenterology
سال: 2010
ISSN: 0036-5521,1502-7708
DOI: 10.3109/00365521003675047