Neuronal Migrations and Axon Fasciculation Are Disrupted in ina-1 Integrin Mutants
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چکیده
منابع مشابه
Neuronal Migrations and Axon Fasciculation Are Disrupted in ina-1 Integrin Mutants
Integrins are heterodimeric cell surface receptors implicated in cell adhesion and signaling. Our analysis of C. elegans ina-1 alpha integrin mutants provides the first genetic evidence that migrating neurons require integrins. Mosaic analysis and expression studies show that ina-1 acts autonomously in cells to promote their migrations. Although axons generally extend to their normal targets in...
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ژورنال
عنوان ژورنال: Neuron
سال: 1997
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)80347-5