Neuromyelitis Optica Spectrum Disorders with Autoimmune Diseases

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منابع مشابه

Neuromyelitis optica spectrum disorders without and with autoimmune diseases

BACKGROUND Neuromyelitis optica spectrum disorder (NMOSD) can coexist with non-organ-specific or organ-specific autoimmune diseases. The aim of this study was to investigate and compare the features between NMOSD without and with autoimmune diseases, and NMOSD with non-organ-specific and organ-specific autoimmune diseases. METHODS One hundred and fifty five NMOSD patients without autoimmune d...

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Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate

BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...

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Neuromyelitis Optica Spectrum Disorders: Diagnosis and Treatment

The last decade has witnessed rapid developments in the clinical understanding and scienti fi c foundati on of neuromyeliti s opti ca (NMO). The landmark events were the late 19th century report by Devic and Gault describing the associati on of severe acute transverse myeliti s and opti c neuriti s and the late 20th century discovery that the syndrome was associated with a specifi c autoanti bo...

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Neuromyelitis optica associated with systemic autoimmune diseases in children

Case reports Neuromyelitis optica (NMO, Devic's disease) is a severe autoimmune disorder predominantly involving optic nerves and spinal cord [1]. Usually isolated, it has been associated with systemic autoimmune diseases in adult patients [2]. We report 2 children with a systemic autoimmune disease who developed NMO. Patients were female; NMO symptoms started at age 8 and 12 years. Patient 1 h...

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Neuromyelitis Optica Spectrum Disorders: a definite case with Autoimmune Thyroiditis CASE REPORT

Case Report: A 24 year-old female was admitted due to a sudden painful hypovision in the left eye. The etiological investigation was negative but brain MRI showed T2 hyperintensity of the left optic nerve with gadolinium enhancement, but no signal changes in the brain parenchyma. Eleven years before, she had been diagnosed with autoimmune thyroiditis based on hypothyroid goiter with biopsy-prov...

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ژورنال

عنوان ژورنال: Journal of Multiple Sclerosis

سال: 2015

ISSN: 2376-0389

DOI: 10.4172/2376-0389.1000167