Neuromyelitis optica spectrum disorder – case report

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Neuromyelitis Optica Spectrum Disorder: A Case Report

A 66 year old woman suffering from recurrent attacks of neuropathic burning pain over the past 6 years, affecting first the sacral region and then progressively different locations on the face, was referred to our facility. She had severe paraparesis and signs of brainstem dysfunction leading to respiratory failures. After an extensive investigation including brain and spinal cord MRI and labor...

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[Neuromyelitis optica spectrum disorder: a case report].

Neuromyelitis optica (NMO) is a relapsing inflammatory disease of the central nervous system, usually affecting the optic nerves and the spinal cord. It is presumed to be an antibody-mediated disorder and the target antigen is the water channel aquaporin-4 (AQP4) on astrocyte cell membranes. NMO is a disease caused by astrocyte disorder and is distinct from multiple sclerosis (MS), which is a p...

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Neuromyelitis optica spectrum disorder: a pediatric case report

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disorder of the central nervous system that predominantly affects the optic nerves and the spinal cord. Magnetic resonance imaging (MRI) has an increasingly important role in differentiating NMOSD from other inflammatory disorders of the central nervous system, particularly multiple sclerosis (MS). Specific antibodies...

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Tumefactive Brain Lesions in Patients with Neuromyelitis Optica Spectrum Disorder

Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct diagnosis.  Clinical P...

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Sleep abnormality in neuromyelitis optica spectrum disorder

OBJECTIVES We investigated the sleep structure of patients with neuromyelitis optica spectrum disorder (NMOSD) and the association of abnormalities with brain lesions. METHODS This was a prospective cross-sectional study. Thirty-three patients with NMOSD and 20 matched healthy individuals were enrolled. Demographic and clinical characteristics of patients were collected. Questionnaires were u...

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ژورنال

عنوان ژورنال: Medical Studies

سال: 2016

ISSN: 1899-1874

DOI: 10.5114/ms.2016.58805